Once you complete your assessment and place an order, our pharmacist will review your details to ensure this treatment is right for you. If approved, we’ll send your medication directly to your doorstep in secure packaging.
Wegovy (semaglutide) is a prescription, once-weekly GLP-1 weight loss injection for adults dealing with a body mass index (BMI) of 30 or higher. This weight loss injectable works by controlling appetite and calorie intake.
It may also be suitable for people with a BMI of 27 who have been diagnosed with weight-related health conditions such as high blood pressure and type 2 diabetes. Clinical trials show that, when combined with diet and exercise, Wegovy helps most people lose 15–20% of their starting body weight over 68 weeks.
Wegovy offers a range of benefits that support both weight management and overall health. The key benefits of Wegovy are:
Sustained weight loss
STEP clinical trials showed an average reduction of 15–20% body weight over 68 weeks.
Most weight loss occurs in the first 20–30 weeks, then plateaus, helping patients maintain results long term.
Reduced appetite and cravings
By activating GLP‑1 receptors, Wegovy slows gastric emptying and signals a feeling of fullness.
Patients report eating smaller portions and fewer snacks between meals.
Improved glycaemic control
Lowers fasting glucose and HbA1c by up to 1.6 percentage points in people with type 2 diabetes.
Reduces insulin resistance, decreasing both blood sugar spikes and dips.
Cardiovascular risk reduction
Weight loss itself lowers blood pressure, LDL cholesterol and triglycerides in the body.
Clinical trials suggest a potential reduction in major adverse cardiovascular events in high‑risk patients.
Enhanced quality of life
Many users report improved mobility and better mood as weight decreases.
Reduced joint pain and sleep apnoea symptoms are common secondary gains.
Mechanism of Action of Wegovy:
GLP‑1 receptor agonist When Semaglutide binds GLP‑1 receptors, it:
Slows gastric emptying
Increases satiety
Stimulates insulin secretion only when glucose levels are high
Suppresses glucagon secretion, preventing excess blood sugar
Central appetite control
Targets brain regions that integrate hunger and reward signals.
Lowers activity in the “reward” pathways that drive overeating of high‑calorie foods.
Wegovy directly suppresses appetite, reducing the desire to eat. It works by mimicking a natural hormone in the body, GLP-1. By functioning like GLP-1, Wegovy helps you feel fuller, leading to significant weight loss.
Semaglutide has proved to be an effective weight loss treatment under STEP trials, with benefits sustained over time when used consistently.
|
Trial Phase |
Population |
Weight Loss vs Placebo |
HbA1c Reduction |
Key Findings |
|
STEP 1 |
Obese adults without diabetes |
–14.9% |
–0.2% |
86% achieved ≥ 5% weight loss and 69% ≥ 10% |
|
STEP 2 |
Overweight/obese with type 2 diabetes |
–9.6% |
–1.6% |
Superior glycaemic control vs titrated comparators |
|
STEP 3 |
Intensive behavioural therapy + Wegovy |
–16.0% |
–0.8% |
Demonstrated additive benefit of structured support |
|
STEP 4 |
Dose‑escalation maintenance study |
–17.4% |
–0.9% |
Showed sustained weight loss when continuing treatment |
Note: Wegovy should be used alongside a reduced-calorie diet and increased physical activity. Always consult a healthcare professional before starting treatment.
Before starting Wegovy, it’s important to understand the potential risks, contraindications, and situations requiring extra care. Always use under the guidance of a qualified healthcare professional.
Always consult a healthcare professional before starting Wegovy. Lifestyle habits and medical history must be carefully reviewed to ensure this treatment is appropriate for you.
The active ingredient in Wegovy is semaglutide.
It resists enzymatic breakdown and binds GLP‑1 receptors to:
These are used to make the medication safe and effective:
Diarrhea
Vomiting
Constipation
Nausea
Stomach pain
Headache
Abdominal discomfort
Belching
Fatigue
Pancreatitis (severe abdominal pain)
Gallbladder disease (cholelithiasis)
Acute kidney injury (accompanied by severe dehydration)
Severe allergic reactions (rash, airway constriction)
Titration:
Slow dose increases help reduce GI upset.
Diet Modifications:
Small meals
Low‑fat foods
Sipping clear fluids to avoid dehydration
Avoid greasy or spicy foods
Symptomatic Relief:
Antiemetics for nausea
Laxatives or fibre supplements for constipation
When to Seek Care:
Sudden severe abdominal pain (pancreatitis risk)
Signs of allergic reaction (hives, swelling, difficulty breathing)
Visual changes or rapid heartbeat
Always discuss persistent or severe symptoms promptly with your healthcare provider.
Exceptional service. We needed medicine for my parents. The pharmacy was able to arrange stock and deliver the medication on the same day. The team really went the extra mile.
Really good staff! Very helpful and prompt. I had a really bad experience at my previous pharmacy, really happy I moved over. Recommend to everyone especially because they’re open 7 days a week even on bank holidays!
I had an excellent experience at Star Pharmacy! The staff is incredibly friendly, knowledgeable, and always willing to help. They go above and beyond to answer questions and ensure you get the right medication. The store is clean, well-organized, and fully stocked with everything you need. Highly recommend this pharmacy for their outstanding customer service!
Excellent pharmacy, quick and kind. Now that I’ve moved house, I still travel all the way here even though I could pick somewhere closer. Just couldn’t go anywhere else!
Always really helpful & so friendly. Even when not dispensing my medicine, the pharmacist has given me second opinion and checked me over. Have ordered me needles in that I had trouble getting elsewhere also. So refreshing to find a pharmacy who wants to help and is kind!
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How to use weight loss injections?
They’re usually taken once a week using a simple pre-filled pen. You inject it yourself, following the step-by-step guidance from our healthcare provider.
Is it safe to use weight loss injections?
Yes, when prescribed and monitored by our professionals at Star Pharmacy. Some people may experience temporary side effects like nausea, headaches, or mild digestive changes.
How long does 1 weight loss injection last?
Each pen contains four doses, so it will last for around one month when used weekly.
Who is eligible for weight loss injections?
Generally for adults with a BMI of 30+, or 27+ if you have weight-related conditions like diabetes or high blood pressure. Your eligibility will be confirmed in a consultation.
Are there any side effects of weight loss medicines?
Possible side effects include nausea, vomiting, diarrhoea, constipation, and mild headaches. These effects are usually temporary and improve as your body adjusts to the medication.
How do I calculate my BMI?
Use the formula: weight (kg) ÷ height (m²), or check with any online BMI calculator for quick results.
What is the injection that helps you lose weight?
Prescription based weight loss injections called a GLP-1 injection help you reduce appetite and help control hunger, making it easier to lose weight and keep it off.
Each Wegovy pen has 4 doses. The dosage begins at 0.25 mg once a week for the first 4 weeks, which is then increased based on individual responses and tolerance, going to a maximum of 2.4 mg once a week.
Wegovy involves a weekly subcutaneous (under the skin) injection in the lower abdomen, thigh or upper arm. Rotate the injection sites each week to avoid irritation or discomfort. At Star Pharmacy, we’ll give you detailed guidance on how to use it.
The benefits you have gained would gradually diminish if you stop taking Wegovy, leading to weight regain. It is essential to consult your healthcare provider before stopping Wegovy so that they can maintain your progress with alternative strategies.
Wegovy is not recommended during pregnancy or breastfeeding. If you are pregnant or breastfeeding, consult your healthcare provider for alternative options to ensure safety.
Wegovy is not recommended to; Adults over 75 years Pregnant and breastfeeding women Anyone with an eating disorder In case of pancreatitis
If it's been 5 days or less, inject as soon as you remember, then resume your regular schedule. If it's been more than 5 days, skip the missed dose and inject on your next scheduled day. Do not take two doses to make up for a missed one.
