E45 Itch Relief Cream

E45 Itch Relief Cream
E45 Itch Relief Cream - Image 2
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E45 Itch Relief Cream

In Stock.

E45 Itch Relief Cream is a clinically proven treatment designed to relieve itchy, dry and irritated skin. It may be caused by eczema, dermatitis or other dry skin conditions. It has a dual-action formula and contains urea to intensely hydrate and lauromacrogols to soothe the itchy skin.

Unlike emollients, this cream is specifically designed for itch management, making it essential for a dry skincare routine. It is suitable for long-term daily use.

✔ Trusted by dermatologists
✔ Steroid-free treatment
✔ Clinically proven itch relief cream

Star Pharmacy offers E45 Itch Relief Cream as part of our specialist dry skin care range. With professional advice, great value, and easy ordering, we help you manage itching and irritation so your skin stays calm, hydrated, and healthy every day.

  • What is E45 Itch Relief Cream?

    E45 Itch Relief Cream is formulated with urea, which draws moisture into the skin, and lauromacrogols, which help calm the skin and interrupt the itch cycle. Itchy skin can impact comfort, sleep and quality of life, especially when linked to skin conditions like eczema or dermatitis. The cream is non-greasy, fragrance-free, and steroid-free, making it safe for everyday use, even on sensitive skin. E45 Itch Relief Cream hydrates, protects, and relieves, making your skin feel smooth and itch-free. Whether used occasionally or every day, the cream offers rapid comfort.

    What are the key benefits of E45 Itch Relief Cream?

  • Soothes itchy, irritated skin
  • Lauromacrogols work quickly to calm the skin and stop the urge to scratch.
  • Hydrates and softens skin
  • Urea draws moisture into the skin, leaving it softer and more supple.
  • Steroid-free
  • Suitable for long-term use without the side effects linked to topical steroids.
  • Non-greasy formula
  • Comfortable to wear during the day without leaving residue.
  • Dermatologist-tested
  • Proven safe for sensitive, dry, and eczema-prone skin.
    • Fragrance-free & hypoallergenic
    Minimises risk of allergic reactions or irritation.

    How Does It Work?

    Moisturising Action:
    • Urea penetrates deep into the skin to attract and lock in moisture.
    • Helps repair the skin barrier to prevent water loss.
    Soothing Action:
    • Lauromacrogols calm nerve endings to reduce the sensation of itching.
    • Reduces redness and irritation caused by scratching.
    Protection:
    • Forms a lightweight protective layer to shield skin from environmental triggers.

    When Should You Use E45 Itch Relief Cream?

    • During flare-ups of itchiness due to eczema, dermatitis, or dryness.
    • After showering or bathing to lock in moisture.
    • Following exposure to cold weather, heating, or air conditioning.
    • Whenever itchiness disturbs your sleep or daily comfort

E45 Itch Relief Cream is suitable for:

  • Adults and children aged 1 and above
  • Adults and the elderly suffering from persistent dry, itchy, or irritated skin
  • For skin conditions such as eczema, dry skin, dermatitis or psoriasis or other chronic dry skin conditions
  • People looking for a non-steroidal itch relief treatment that can be used regularly without the risks associated with corticosteroids
  • People experiencing seasonal or environmental dryness (e.g., winter weather, excessive air conditioning, or central heating)
  • Patients recovering from skin flare-ups who want to reduce irritation and prevent recurrence
  • Safe for long-term and daily use

Not suitable for:

  • Avoid using on skin and broken skin unless advised by a healthcare provider
  • Children under 1 year old, unless specifically advised by a doctor, pharmacist, or healthcare professional.
  • Broken, infected, or bleeding skin unless under medical supervision.
  • Individuals with a known allergy to lauromacrogols, urea, or any other listed ingredient.
  • Application on mucous membranes (e.g., eyes, mouth, inside the nose, or genital area) unless instructed by a healthcare provider.
  • For external use only, do not ingest.
  • Do not use open wounds, broken or infected skin, unless advised by a healthcare professional
  • Avoid contact with the eyes, mouth and inside the nose. If accidental contact occurs, rinse thoroughly with clean water.
  • Keep out of sight and reach of children to prevent accidental ingestion or misuse.
  • Keep away from direct sunlight
  • Always read instructions before use
  • Do not use if you are allergic or hypersensitive to any of the listed ingredients, especially lauromacrogols or urea
  • Stop using it immediately if you notice redness, swelling, rash, burning, or worsening skin irritation, and seek medical advice
  • If your symptoms do not improve within 2 weeks of regular use, consult your doctor or pharmacist
  • Store in a cool, dry place, away from direct heat and sunlight, and keep the cap tightly closed after each use
  • Use caution when applying to large body areas or under occlusive dressings unless advised by a healthcare professional

Additional Cautions

  • If you are pregnant or breastfeeding, consult your doctor before use.
  • Avoid using multiple topical treatments in the same area unless approved by a healthcare provider, to prevent interactions or irritation.
  • In rare cases, some individuals may experience a temporary tingling or mild stinging sensation after application; this should ease as your skin adjusts.

Lifestyle & Skin Care Tips 

  • Moisturise regularly with E45 Itch Relief Cream as part of a daily skincare routine, ideally after bathing when skin is still slightly damp.
  • Use lukewarm water instead of hot water when showering or bathing, to prevent further skin dryness.
  • Choose mild, fragrance-free cleansers instead of harsh soaps.
  • Wear loose-fitting, breathable clothing to reduce friction and overheating of the skin.
  • Maintain a humid environment indoors during winter or when heating is on, to help prevent skin from drying out.
  • Stay hydrated and eat a balanced diet rich in omega-3 fatty acids (e.g., oily fish, flaxseed) to support skin health from within.

Step-by-Step Application

  • Clean the Affected Area
        • Wash your hands and gently cleanse the skin with lukewarm water or a mild, fragrance-free cleanser.
        • Pat the area dry with a soft towel and avoid rubbing, which can worsen irritation.
  • Apply a Thin Layer
        • Squeeze a small amount of cream onto clean fingertips.
        • Smooth gently over the affected area, using light circular motions until fully absorbed.
  • Frequency of Use
        • Use two to three times daily or as often as needed to relieve itch and dryness.
        • For persistent dryness, apply immediately after bathing or showering to lock in moisture.
  • After Application
      • Wash your hands after application to avoid accidental transfer into the eyes or mouth.

    Tips for Best Results

    • Apply regularly rather than only when symptoms flare, to help maintain the skin’s moisture barrier.
    • Avoid hot showers or baths, as these can strip the skin of natural oils and worsen dryness.
    • Use alongside gentle, fragrance-free soaps and laundry detergents to reduce skin irritation.
    • Wear loose-fitting, breathable clothing (e.g., cotton) to prevent friction on irritated areas.
    • Do not double the amount to make up for a missed application.

    Regular use is key to maintaining skin comfort, particularly during flare-ups or in cold, dry weather.

Active Ingredients:

  • Urea (5%) 

It hydrates the skin by drawing moisture into the skin

  • Lauromacrogols (3%) 

Acts as a local anaesthetic to reduce itching

Other Ingredients:

  • Light liquid paraffin
  • White soft paraffin
  • Glycerol monostearate
  • Cetyl alcohol
  • Sodium lactate
  • Purified water

It is free from:

  • Fragrance
  • Steroids
  • Colourants

Possible Side Effects

E45 Itch Relief Cream is generally well tolerated by most users and has a low risk of adverse effects when used as directed. However, as with all topical skincare products, side effects can occur in rare cases. These may include:

  • Mild Skin Irritation

Redness, dryness, or discomfort at the site of application, usually mild and temporary.

  • Temporary Stinging or Burning Sensation

Tingling or warmth may occur, particularly if the skin is very dry, cracked, or inflamed.

  • Allergic Reactions

Rash, itching, swelling, blistering, or peeling skin. This can happen if you are sensitive to any of the ingredients.

  • Exacerbation of Symptoms

In rare cases, skin irritation or itchiness may worsen rather than improve.

  • Contact Dermatitis

Localised rash or inflammation triggered by an allergic or irritant response to the product.

What to Do if Side Effects Occur

  • Stop using the cream immediately.
  • Wash the affected area with mild, fragrance-free soap and lukewarm water.
  • Apply a soothing, hypoallergenic moisturiser if needed.
  • Seek medical advice promptly if symptoms persist, spread, or worsen.

Seek Immediate Medical Attention If You Experience:

  • Difficulty breathing, dizziness, or swelling of the face, lips, tongue, or throat (signs of a severe allergic reaction).
  • Extensive blistering or oozing skin.

Reviews

user

Adam

Exceptional service. We needed medicine for my parents. The pharmacy was able to arrange stock and deliver the medication on the same day. The team really went the extra mile.

user

Galaxy 24

Really good staff! Very helpful and prompt. I had a really bad experience at my previous pharmacy, really happy I moved over. Recommend to everyone especially because they’re open 7 days a week even on bank holidays!

user

Aleena W

I had an excellent experience at Star Pharmacy! The staff is incredibly friendly, knowledgeable, and always willing to help. They go above and beyond to answer questions and ensure you get the right medication. The store is clean, well-organized, and fully stocked with everything you need. Highly recommend this pharmacy for their outstanding customer service!

user

Rachel

Excellent pharmacy, quick and kind. Now that I’ve moved house, I still travel all the way here even though I could pick somewhere closer. Just couldn’t go anywhere else!

user

Krystal Clair

Always really helpful & so friendly. Even when not dispensing my medicine, the pharmacist has given me second opinion and checked me over. Have ordered me needles in that I had trouble getting elsewhere also. So refreshing to find a pharmacy who wants to help and is kind!

How it Works

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Enjoy a one-to-one consultation with our expert. We’ll review your symptoms and history to recommend the safest treatment.

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FAQs

How to use weight loss injections?

They’re usually taken once a week using a simple pre-filled pen. You inject it yourself, following the step-by-step guidance from our healthcare provider.

Yes, when prescribed and monitored by our professionals at Star Pharmacy. Some people may experience temporary side effects like nausea, headaches, or mild digestive changes.

Each pen contains four doses, so it will last for around one month when used weekly.

Generally for adults with a BMI of 30+, or 27+ if you have weight-related conditions like diabetes or high blood pressure. Your eligibility will be confirmed in a consultation.

Possible side effects include nausea, vomiting, diarrhoea, constipation, and mild headaches. These effects are usually temporary and improve as your body adjusts to the medication.

Use the formula: weight (kg) ÷ height (m²), or check with any online BMI calculator for quick results.

Prescription based weight loss injections called a GLP-1 injection help you reduce appetite and help control hunger, making it easier to lose weight and keep it off.

E45 Itch Relief Cream is used to relieve itching and inflammation caused by eczema, dermatitis, or dry skin conditions.

E45 Itch Relief Cream contains lauromacrogols to soothe itching and urea to hydrate and soften dry, irritated skin.

Apply 2–3 times daily or as directed by a healthcare provider. Reapply as needed for ongoing itch relief.

Yes, but it is generally recommended for children over 1 year. Check with a healthcare provider for infants or long-term use.

Yes, E45 Itch Relief Cream is considered safe to use during pregnancy and breastfeeding. Avoid applying to the breast area before feeding.

Avoid applying it to broken, bleeding, or infected skin unless directed by a healthcare professional.

Side effects are rare but may include mild stinging, redness, or irritation. Discontinue use if reactions occur.

Yes, but leave time between applications and apply medicated creams before moisturisers unless otherwise advised.

Store at room temperature, in a dry place away from direct sunlight. Keep out of reach of children.